稲田　全規

Professional Career

経歴

2005年～2010年 : ハーバード大学医学部 ビジティング フェロー
2006年～2007年度 : 東京農工大学, 大学院・共生科学技術研究院, 講師
2008年～現在 : 国立大学法人 東京農工大学 准教授
2012年～現在 : 早稲田大学 客員准教授
2016年～現在 : 日本歯科大学 客員教授
2017年～現在 : 国立精神神経疾患研究センター 客員研究員

Academic Degrees

学位

1997年 博士（歯学）日本歯科大学大学院

Research Interests

キーワード

廃用性筋萎縮、骨粗鬆症、骨転移癌、マトリックスメタロプロテアーゼ

Publications

論文

• Tominari T, Matsumoto C, Tanaka Y, Shimizu K, Takatoya M, Sugasaki M, Karouji K, Kasuga U, Miyaura C, Miyata S, Itoh Y, Hirata M, Inada M, Roles of Toll-like Receptor Signaling in Inflammatory Bone Resorption. BIOLOGY-BASEL, 2024 13:692. doi: 10.3390/biology13090692.

• Urano K, Tanaka Y, Tominari T, Takayoya M, Arai D, Miyata S, Matsumoto C, Miyaura C, Numabe Y, Itoh Y, Hirata M and Inada M, The stiffness and collagen control differentiation of osteoclasts with an altered expression of c-Src in podosome. Biochemical and Biophysical Research Communication (B.B.R.C.) vol704, 149636 (2024)

• Tominari T., Takatoya M., Matsubara T, Matsunobe M., Arai D., Matsumoto C., Hirata M., Yoshinouchi S., Miyaura C., Itoh Y., Komaki H., Takeda S., Aoki Y., InadaM., Establishment of a quantitation method using triple quadrupole HPLC-MS quantitation method for dystrophin protein in mouse and human skeletal muscle. International Journal of Molecular Sciences (Int. J. Mol. Sci.) 2024, 25(1), 303.

• Yoshinouchi S, Karouji K, Tominari T, Sugasaki M, Matsumoto C, Miyaura C, Hirata M, Itoh Y, Inada M. Prostate cancer expressing membrane-bound TGF-α induces bone formation mediated by the autocrine effect of prostaglandin E2in osteoblasts. Biochemical and Biophysical Research Communications. 2023.12;644:40-48. doi: 10.1016/j.bbrc.2022.11.050.

• Tanaka, R., Yoshinouchi, S., Karouji, K., Tanaka, Y., Tominari, T., Hirata, M., Matsumoto, C., Itoh, Y., Miyaura, C., Inada, M. A mouse model of lung cancer induced via intranasal injection for anti-cancer drug screening and evaluation of pathology. FEBS Open Bio. 2022. 13 (1), 51-59

• Tominari T, Akita M, Matsumoto C, Hirata M, Yoshinouchi S, Tanaka Y, Karouji K, Itoh Y, Maruyama T, Miyaura C, Numabe Y, Inada M. Endosomal TLR3 signaling in stromal osteoblasts induces prostaglandin E2-mediated inflammatory periodontal bone resorption. Journal of Biological Chemistry (J. Biol. Chem.): 298-3, 101603, 2022

• Tominari, T., Sanada, A., Ichimaru, R., Matsumoto, C., Hirata, M., Itoh, Y., Numabe, Y., Miyaura, C., Inada, M. Gram-positive bacteria cell wall-derived lipoteichoic acid induces inflammatory alveolar bone loss through prostaglandin E production in osteoblasts. Scientific Reports (Sci Rep.). (11):13353, 2021
• Itoh Y, Ng M, Wiberg A, Inoue K, Hirata N, Paiva KBS, Ito N, Dzobo K, Sato N, Gifford V, Fujita Y, Inada M, Furniss D. A common SNP risk variant MT1-MMP causative for Dupuytren’s Disease has a specific defect in collagenolytic activity. Matrix Biology, 97, 29-30, 2021
• Aharen I, Habash SS, Gleason C, Inada M, Grundler FM, Elashry A. Heterodera schachtii glutathione peroxidase (HsGPx) is a parasitism protein. Journal of Plant Diseases and Protection. 127.111-118, 2020
• Tominari T, Ichimaru R, Taniguchi K, Yumoto A, Shirakawa M, Matsumoto C, Watanabe K, Hirata M, Itoh Y, Shiba D, Miyaura C, Inada M. Hypergravity and microgravity exhibited reversal effects on the bone and muscle mass in mice. Scientific reports. 9(1):6614, 2019
• Hirata N , Ichimaru R , Tominari T , Matsumoto C, Watanabe K ,Taniguchi K , Hirata M , Ma S, Suzuki K , Grundler FM , Miyaura C, Inada M. Beta-Cryptoxanthin Inhibits Lipopolysaccharide-Induced Osteoclast Differentiation and Bone Resorption via the Suppression of Inhibitor of NF-B Kinase Activity. Nutrients. 11.2.368
• Aizawa M, Watanabe K, Tominari T, Matsumoto C, Hirata M, Grundler FM, Inada M, Miyaura C. Low Molecular-Weight Curdlan, (1 -> 3)-beta-Glucan Suppresses TLR2-Induced RANKL-Dependent Bone Resorption. Biological and Pharmaceutical Bulletin (Biol. Pharm. Bull.) . 41:1282-1285, 2018