イベント情報
【GIR公開セミナー】Dr. Takeshi Harayama / Institute of Molecular and Cellular Pharmacology – CNRS, コートダジュール大学（フランス）
| 日時 | 2024.11.29（17：00～18：00） |
|---|---|
| 会場 | |
| 講演者 | Dr. Takeshi Harayama |
| 所属機関 | Institute of Molecular and Cellular Pharmacology – CNRS, コートダジュール大学 （フランス） |
| 講演タイトル | "Connecting lipid tail structures to cellular functions" ＜要旨＞ Cellular membranes are composed of a diverse set of lipids with tails that vary significantly in chain lengths, the number of double bonds and the positions of these double bonds. Although lipids with uniform tails are sufficient to make bilayers in vitro, the diversity in lipid tail structures is seen across the tree of life, suggesting the biological importance of having lipids with distinct tails. It is critical to decode the functional relevance of lipid tails to understand the basic architecture of our cells, and to correctly assess the importance of lipidome changes that are seen in various diseases. For this, we are developing tools that combine genetics and synthetic lipid feeding to manipulate the tail composition of membrane lipids in cells, allowing us to study their consequences. In this seminar, I will discuss how an optimal combination of lipid head groups and tails is generated in cells, and how they contribute to cellular processes, such as ferroptosis, which is a lipid peroxidation-dependent cell death. |
| 言語 | 英語 |
| 対象 | どなたでも、ご参加いただけます。 |
| 共催 | グローバルイノベーション研究院 ライフサイエンス分野 川野チーム 卓越大学院プログラム |
| お問い合わせ窓口 | グローバルイノベーション研究院・工学研究院 津川 裕司 e-mail: htsugawa（ここに@ を入れてください）go.tuat.ac.jp |
| 備考 | 本セミナーは、対面型のみの開催となります。 |
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