イベント情報
【GIR公開セミナー】 Dr. Naoki Yamanaka / カリフォルニア大学 リバーサイド校 （米国） “Transporter-mediated steroid hormone transport across cell membranes”
| 日時 | 2019.12.18（16：30～17：30） |
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| 会場 | |
| 講演タイトル | ◆Dr. Naoki Yamanaka (Assistant Professor, Department of Entomology, University of California, Riverside, U.S.A.) "Transporter-mediated steroid hormone transport across cell membranes" 〈要旨〉 The insect steroid hormone ecdysone induces molting and metamorphosis through its interaction with intracellular nuclear receptors. Although it has long been assumed that all steroid hormones can enter their target cells by simple diffusion, we recently demonstrated in the fruit fly Drosophila that a membrane transporter named Ecdysone Importer (EcI) is required for cellular uptake of ecdysone (Okamoto et al., Dev Cell 2018). To further explore physiological significance of transporter-mediated steroid hormone entry into cells, we continued our study and found that EcI has a critical role in the blood-brain barrier during Drosophila brain development. I will present our most recent results and discuss the importance of the steroid hormone importer in insect development and beyond. |
| 言語 | 英語 |
| 対象 | どなたでも、ご聴講いただけます。 |
| 共催 | グローバルイノベーション研究院 ライフサイエンス分野 篠原チーム 卓越大学院プログラム |
| 開催概要 | |
| お問い合わせ窓口 | グローバルイノベーション研究院・工学研究院 川野竜司 e-mail: rjkawano (ここに@ を入れてください） cc.tuat.ac.jp |
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